



True beauty is found in the details, which is why founder Melissa Donelson, MSN, RN, CRNP, personally oversees every aspect of your care. We offer customized weight loss solutions and aesthetic treatments designed to help you look and feel your best. Our telehealth services allow patients across the country to access the same high level of medical expertise and one-on-one coaching found in our Maryland clinic.
Discover your natural beauty and confidence at MD Optimal Health & Aesthetics. We believe that dedicated self-care, guided by our expertise, can unlock your inherent confidence and beauty.


Weight loss is a deeply personal journey. From the early struggles to the ultimate victory of losing 100 pounds, Melissa Donelson, CRNP, understands that weight loss is rarely a simple "calories in, calories out" equation.
It involves navigating hormones, habits, and your unique medical history. These intricacies are like a recipe to your lasting health and wellness — one that Melissa will help you find and follow for lasting results. Our virtual weight loss program merges Melissa’s 30+ years of clinical experience with one-on-one coaching to help you understand triggers and build sustainable behaviors that last. Access tailored medical and nutrition support, including GLP-1 medications through DrWell, professional-grade vitamin therapy, and meal replacement plans through Medi-Weightloss, all personally curated to your body’s unique needs. Melissa will design a weight loss plan that makes sense for your body, provide unwavering support through every challenge, and guide you through the small victories that lead to life-changing results. If you are ready for a weight loss plan that works, take the first step with a virtual consultation today.
With a career spanning 30 years in medicine, Melissa Donelson, MSN, RN, CRNP, has dedicated her life to helping patients live better lives.
As a board-certified Nurse Practitioner with a background in acute care, she understands the intricate systems of the human body. Melissa opened MD Optimal Health & Aesthetics to offer a refuge of personalized, one-on-one aesthetic and wellness care. She believes that the best results come from a provider who truly listens and understands. This belief was solidified when she faced her own significant health and weight loss hurdles, changing her perspective forever.
Melissa understands the complexities of weight loss through her own lifelong journey. She achieved significant and lasting success starting in 2021 by focusing on the crucial elements of mindset, eating habits, triggers, and healthy behaviors. Having lost and kept off over 100 pounds, she brings a deep sense of empathy and invaluable personal insight to her coaching, coupled with her extensive medical knowledge.
Melissa is adept at supporting clients with intricate medical histories, including those who have previously undergone weight loss surgery. Her dedication has empowered hundreds of patients to reach their weight loss goals. Melissa provides personalized guidance through both in-person and virtual appointments available in multiple states.








Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
Give your skin a reason to glow by stimulating its own natural healing power. This treatment creates tiny, controlled pathways in the skin to trigger collagen production without the downtime of more aggressive procedures. It is an excellent choice for improving texture, fine lines, and even thinning hair. Your skin will look smoother, firmer, and more refreshed.
Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
Lose weight with a plan that actually fits your life. Our program combines medical expertise, personal coaching, effective medications, and nutrition to help you shed pounds safely. We are here to guide you through every victory (and every challenge) along the way. Whether in-person or virtual, your journey is completely customized to your biology.
Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
Smooth away the signs of stress and aging with your own precisely tailored injectable plan. We develop a unique injectable "recipe" based on your facial muscle movement to ensure you still look like yourself, only more rested. By tracking your results over time, we achieve a look that is consistently natural. Our Botox treatments offer the perfect way to refresh your appearance with confidence and ease.
Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
Reveal a brighter, more even complexion by gently removing the dull outer layers of skin. Options like the ZO stimulator peel address sun damage, acne scars, and fine lines with clinical precision. You will leave feeling renewed and revitalized.
Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
Restore lost volume and refine your features with our selection of premium dermal fillers. We use a gentle touch and the latest techniques to subtly enhance your cheeks, lips, or under-eye area. The goal is always balance and harmony, making you look younger without looking "done." We use only the most effective, verified products to ensure a safe treatment and results you love.
Microchanneling
Medical Weight Loss
Botox
Chemical Peels
Dermal Fillers
Skin Care Solutions
High-quality results require high-quality support at home. We curate professional-grade skin care solutions from lines like ZO Skin Health and PRX Derm Perfexion that work in tandem with your in-office treatments to protect your investment. From potent serums to daily essentials, we find the right products for your specific skin type and goals. This is about building a sustainable routine for long-term skin health.



You deserve a provider who is as invested in your results as you are. Melissa’s philosophy is simple: provide expert-level care in a warm, approachable environment. She takes the complexity out of aesthetics and wellness, explaining the why behind your treatment plan.
Drawing on her own health journey, she offers herself as a knowledgeable, empathetic guide for yours. By managing every step of your care herself, Melissa tracks your progress with incredible attention to detail, from your personalized wellness “recipe” to your weight loss milestones. Her support extends beyond a single treatment. She focuses on creating a long-term partnership to rebuild the foundation of your health and confidence.
Everyone deserves to feel confident and vibrant. Because life is busy and budgets vary, we offer flexible payment options through Cherry. Choose a payment plan that works for you, including 0% APR options for those who qualify. There are no hard credit checks to apply, and the process takes only a few seconds. Let’s focus on achieving the results you desire in a way that makes sense for your lifestyle.


Browse through our gallery of real patient results.